Beilstein J. Nanotechnol.2015,6, 111–123, doi:10.3762/bjnano.6.11
using an easy, on demand, exchange-labeling technique and their particokinetic parameters were studied in mice after intravenous injection. The results indicate that the application of these heterologous isotopes can be used to successfully mark the nanoparticles during initial distribution and organ
uptake, although the 65Zn-label appeared not to be fully stable. As the degradation of the nanoparticles takes place, the individual transport mechanisms for the different isotopes must be carefully taken into account. Although this variation in transport paths can bring new insights with regard to the
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Figure 1:
Postsynthetic labeling of quantum dots or SPIOs by incubation of monodisperse, oleic acid-stabilize...
Beilstein J. Nanotechnol.2015,6, 36–46, doi:10.3762/bjnano.6.5
vivo for the respective nanoparticle uptake.
Keywords: albumin; 59Fe; 125I; organuptake; protein corona; SPIOs; transferrin; Introduction
Nanoparticles (NPs) have unique capabilities to interact with cells and organs which mark them as attractive working material in nanobioscience and nanomedicine
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Figure 1:
Synthesis and characterization of polymer-coated SPIOs with different surface charge due to PEGylat...